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What causes IgA nephropathy?

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Post time 2018-06-10 06:22:37 | Show all posts |Read mode
IgA nephropathy is mainly caused by autoimmune disorders which means the IgA immune globulin goes wrong.The diseased IgA immune globulin will combine with autoantibody to form immune complex that may deposited in the GMA.In addition that the GMA has some affinity with these immune complex.The deposition of immune complex will secrete inflammatory factors,as the disease worsen,the damage is related to kidneys.What's worse,the damaged kidneys may result in renal failure.
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